13 results
Lupus Nephritis Classification Algorithm

#Lupus #Nephritis #Classification #Algorithm #diagnosis #differential #types #rheumatology #nephrology #renal
Lupus Nephritis ... #Algorithm #diagnosis ... #differential #types ... #rheumatology # ... nephrology #renal
Renal Involvement in Systemic Lupus Erythematosus

Dr. Laurent ARNAUD @Lupusreference

#Renal #diseases #SLE #Systemic #Lupus #Erythematosus #venn #nephrology
Involvement in Systemic Lupus ... SLE #Systemic #Lupus ... Erythematosus #venn #nephrology ... #nephritis #classification ... #types #rheumatology
Renal involvement in 35% of mixed cryoglobulinemia vasculitis 
Associated with : 
 • Absence of skin
neuropathy • Type ... min/1.73 m2 at diagnosis ... • Tendency for nephrotic ... Vasculitis #Management #Rheumatology ... #Nephrology
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Types: • Type ... Labs/Diagnosis: ... (e.g. systemic lupus ... Cryoglobulins #diagnosis ... #rheumatology #
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
Post-strep GN, Lupus ... Nephritis, Cryoglobulinemia ... #differential #diagnosis ... #algorithm #rheumatology
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
Mnemonic C - Cryoglobulinemia ... 1 (50%-80%), type ... S - Systemic Lupus ... CHAMPS #Mnemonic #diagnosis ... #differential #hematology
Rapidly Progressive Glomerulonephritis (RPGN) 
 - Loss of kidney function over a short period of tirne
IgA nephropathy, lupus ... nephritis, cryoglobulinemia ... autoAb against type ... #Differential #Diagnosis ... #Nephrology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... Non-autoimmune rheumatologic ... Kikuchi disease • Type-I ... Erythematosus #Diagnosis ... #Rheumatology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
• Neutrophilic dermatosis ... WM: Vasculitis (Cryoglobulinemic ... to cold IgG • Lupus ... Subcorneal pustular dermatosis ... #Differential #Diagnosis
Recommended initial testing for patients being evaluated for glomerular disease 

24-hour urine collection - Quantify proteinuria.
factor - Screen for cryoglobulinemias ... (types 2 and 3) ... testing #workup #diagnosis ... glomerulonephritis #nephrotic ... #nephritic #nephrology