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differential classification renal vasculitis workup disease glomerular glomerulonephritis hematology nephritis nephrotic algorithm arthritis champs complement cryoglobulinemic cryoglobulins hypocomplementemia initial involvement
Lupus Nephritis Classification Algorithm #Lupus #Nephritis #Classification #Algorithm #diagnosis #differential #types #rheumatology #nephrology #renal
Lupus Nephritis ... Classification #Algorithm #diagnosis ... #differential #types ... #rheumatology # ... nephrology #renal
Renal involvement in 35% of mixed cryoglobulinemia vasculitis Associated with : • Absence of skin
neuropathy • Type ... min/1.73 m2 at diagnosis ... • Dialysis at diagnosis ... Vasculitis #Management #Rheumatology ... #Nephrology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Types: • Type ... Labs/Diagnosis: ... (e.g. systemic lupus ... Cryoglobulins #diagnosis ... #rheumatology #
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Mnemonic C - Cryoglobulinemia ... 1 (50%-80%), type ... S - Systemic Lupus ... CHAMPS #Mnemonic #diagnosis ... #differential #hematology
Rapidly Progressive Glomerulonephritis (RPGN) - Loss of kidney function over a short period of tirne
IgA nephropathy, lupus ... nephritis, cryoglobulinemia ... autoAb against type ... #Differential #Diagnosis ... #Nephrology
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
Differential Diagnosis ... Behcet disease, Cryoglobulinemia ... Complex: Systemic lupus ... Disease-specific testing ... #nephrology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Neutrophilic dermatosis ... WM: Vasculitis (Cryoglobulinemic ... to cold IgG • Lupus ... Subcorneal pustular dermatosis ... #Differential #Diagnosis
Recommended initial testing for patients being evaluated for glomerular disease 24-hour urine collection - Quantify proteinuria.
Recommended initial testing ... factor - Screen for cryoglobulinemias ... (types 2 and 3) ... #workup #diagnosis ... nephrotic #nephritic #nephrology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... ANCA +MPO) • Cryoglobulinemic ... inflammation Others: • Lupus ... such as systemic lupus ... #rheumatology #
Recommended initial testing for patients being evaluated for glomerular disease 1) 24-hour urine collection - Quantify proteinuria.
Recommended initial testing ... factor - Screen for cryoglobulinemias ... (types 2 and 3) ... disease #workup #diagnosis ... #nephrology #nephrotic
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