9 results
Renal Involvement in Systemic Lupus Erythematosus

Dr. Laurent ARNAUD @Lupusreference

#Renal #diseases #SLE #Systemic #Lupus #Erythematosus #venn #nephrology
Lupus Erythematosus ... #Lupus #Erythematosus ... #venn #nephrology ... classification #types ... #rheumatology
Hypersensitivity: Summary
Type I Hypersensitivity:
 • Immunological Mediator: lgE
 • Immunological Target: Allergen Molecules
 • Ex: Antibiotic
Hypersensitivity: Summary Type ... conjunctivitis Type ... complexes • Ex: Systemic ... Lupus Erythematosus ... Syndrome, Contact Dermatitis
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
Causes of Hypocomplementemia ... 1 (50%-80%), type ... glomerulonephritis (>90%) S - Systemic ... Lupus Erythematosus ... #differential #hematology
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
When the specific allergen ... - Local and systemic ... arthritis, and systemic ... lupus erythematosus ... - Contact dermatitis
Vesiculobullous Skin Rash - Differential Diagnosis Algorithm
Vesicles Fragile/EasiIy Ruptured - Intraepidermal blisters, possibly crusts/erosions
 - Inflammatory
• Contact dermatitis ... • Bullous systemic ... lupus erythematous ... Vesiculobullous #SkinRash ... #dermatology #Differential
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
Reactive: - Systemic ... Inflammatory • Systemic ... Lupus Erythematosus ... • Acne • Allergy ... Algorithm #Causes #Hematology
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Mechanism of Action: Allergen-specific ... glomerulonephritis, Systemic ... lupus erythematosus ... Examples: Contact dermatitis ... #allergy #table
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Urticaria and hypocomplementemia ... inflammation Others: • Lupus ... ischemia - Skin: erythematous ... lupus erythematosus ... differential #diagnosis #rheumatology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
febrile neutrophilic dermatosis ... such as certain types ... CANDLE syndrome - Allergic ... ’s syndrome - Lupus ... Syndrome #diagnosis #dermatology