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management oncology algorithm ana antinuclear apml cancer classification dermatology differentiation erythematosus gravis hemophagocytic hlh lymphohistiocytosis myasthenia neurology patterns polychondritis relapsing
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
clinically significant ... SLE), Sjogren's Syndrome ... Lymphoproliferative Disorders, Infection ... ANA #patterns #rheumatology ... #diagnosis #differential
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Classification: • Acute ... permanent alopecia Differential ... fibromyalgia) • Infections ... #Rheumatology
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
life-threatening Differential ... myasthenia Diagnosis ... aspiration and acute ... failure - Can be ... precipitated by: Drugs, infection
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... febrile neutrophilic dermatosis ... initiation • Differential ... Diagnosis: Infection ... #management #hematology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Acute febrile ... neutrophilic dermatosis ... - Lupus - Leukemia ... Treatment: - Systemic ... #diagnosis #dermatology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... syndrome associated ... presents as an acute ... should be diagnosed ... #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
inflammation Others: • Lupus ... such as systemic lupus ... to exclude are infections ... C-ANCA) pattern: antibodies ... #diagnosis #rheumatology
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
the most common clinical ... : • Clinical tests ... Anti-Matrilin-1 Ab ○ Antibodies ... affected tissue Treatment ... Polychondritis #rheumatology
Myelodysplastic syndromes current treatment algorithm 2018. From Blood Cancer Journal, Published 24 May 2018 Myelodysplastic syndromes (MDS) are
clonal evolution to acute ... median age at diagnosis ... may result in an infection ... importance of clinical ... #algorithm #hematology
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