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neurology erythematosus sle systemic antinuclear apml cerebritis cns differentiation gbs gravis guillain hemophagocytic hlh immune inflammatory iris lymphohistiocytosis myasthenia oncology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Demyelinating Syndrome ... Meningitis, Myelopathy, Encephalopathy ... #rheumatology # ... #management #treatment
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
• +ANA can be seen ... clinically significant ... Lymphoproliferative Disorders, Infection ... #rheumatology #diagnosis ... #differential
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... permanent alopecia Differential ... Diagnosis: • ANCA-associated ... fibromyalgia) • Infections ... #Rheumatology
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
life-threatening Differential ... acute respiratory ... failure - Can be ... precipitated by: Drugs, infection ... #management #neurology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... febrile neutrophilic dermatosis ... initiation • Differential ... Diagnosis: Infection ... #management #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... syndrome associated ... should be diagnosed ... #management #treatment ... #hematology
Guillain-Barré Syndrome (GBS) Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness Epidemiology: • Incidence: 1
Guillain-Barré Syndrome ... (GBS) Acute autoimmune ... cauda equina TREATMENT ... #Syndrome #diagnosis ... #management #neurology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Posterior Reversible Encephalopathy ... Reversible course Differential ... , ADEM, Acute toxic ... #Syndrome #diagnosis ... #management #neurology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... initiation Clinical ... albicans • Epstein Barr ... #Differential # ... Diagnosis #Management
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
Anti-Matrilin-1 Ab ○ Antibodies ... Nonspecific ↑ ESR, CRP, ANA ... affected tissue Treatment ... Polychondritis #rheumatology ... #diagnosis #management
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