6 results
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
Post-strep GN, Lupus ... With associated pulmonary ... #Vasculitis #differential ... #diagnosis #algorithm ... #rheumatology
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
alveolar hemorrhage + Glomerulonephritis ... symptomatology Differential ... Diagnosis for Pulmonary ... Complex: Systemic lupus ... #diagnosis #nephrology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Vasculitides - Differential ... Diagnosis Framework ... inflammation Others: • Lupus ... such as systemic lupus ... #diagnosis #rheumatology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... febrile neutrophilic dermatosis ... Imaging: CXR- pulmonary ... initiation • Differential ... Renal Failure Treatment
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... Diagnosis Framework ... Diagnosis: • Systemic ... - interstitial keratitis ... #Diagnosis #Rheumatology
Anti-GIomeruIar Basement Membrane Disease (Goodpasture's Disease)

What is it? A small vessel vasculitis with circulating antibodies directed
rapidly progressive glomerulonephritis ... kidney biopsy Treatment ... #Goodpastures #AntiGBM ... #diagnosis #nephrology ... #pulmonary