10 results
Renal Involvement in Systemic Lupus Erythematosus

Dr. Laurent ARNAUD @Lupusreference

#Renal #diseases #SLE #Systemic #Lupus #Erythematosus #venn #nephrology
Lupus Erythematosus ... #Lupus #Erythematosus ... #venn #nephrology ... #nephritis #classification ... #types #rheumatology
Hypersensitivity: Summary
Type I Hypersensitivity:
 • Immunological Mediator: lgE
 • Immunological Target: Allergen Molecules
 • Ex: Antibiotic
Gravis, Graves' Disease ... complexes • Ex: Systemic ... Lupus Erythematosus ... Syndrome, Contact Dermatitis ... (ie. reaction to
Vesiculobullous Skin Rash - Differential Diagnosis Algorithm
Vesicles Fragile/EasiIy Ruptured - Intraepidermal blisters, possibly crusts/erosions
 - Inflammatory
Bullous impetigo - Reaction ... • Contact dermatitis ... • Bullous systemic ... lupus erythematous ... Vesiculobullous #SkinRash
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... • Type-I Interferonopathies ... Neuropsychiatric systemic ... lupus erythematosus ... #Lupus #Erythematosus
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
hypersensitivity reactions ... , Haemolytic disease ... glomerulonephritis, Systemic ... lupus erythematosus ... Examples: Contact dermatitis
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
- Local and systemic ... during hemolytic disease ... lupus erythematosus ... - Contact dermatitis ... Allergy #Diagnosis #Reactions
Lupus Nephritis - Diagnostic approach to kidney disease associated with systemic lupus erythematosus (SLE)
SLE patient develops
Lupus Nephritis ... approach to kidney disease ... associated with systemic ... lupus erythematosus ... algorithm #sle #nephrology
Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
Manifestations • Optic neuritis ... mainly AQP4-lgG disease ... autoimmune disorders (Systemic ... lupus erythematosus ... Manifestations #diagnosis #neurology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
inflammation Others: • Lupus ... ischemia - Skin: erythematous ... lesions-interstitial keratitis ... lupus erythematosus ... , drug reactions
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
reconstituted immune system ... worsening of that disease ... superinfection, drug reactions ... Related to the type ... granulomatous nephritis