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differential hematology causes palpable cold ddxof deficiency disease extravascular ferritin hemolysis intravascular iron nonpalpable normocytic petechiae rash rheumatology testing workup
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
AIHA Primary Secondary ... lymphoproliferative disorder Secondary ... Diagnosis: • hemolytic ... anemia • Cold ... #anemia #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... anemia): ... thrombocytopenic purpura ... . primary cold agglutin ... #hematology #anemia
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
- Differential Diagnosis ... Algorithm Decreased ... Hypersplenism • Secondary ... #Algorithm #Causes ... #Hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential Diagnosis ... Algorithm • Sickle ... Agglutination - Cold agglutinins ... #Diagnosis #Algorithm
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Diagnosis Framework ... leakage of RBC's secondary ... DIC/TTP/HUS - Hemolytic ... anemia - Splenomegaly ... #Differential #Diagnosis
Petechiae/Purpura - Diagnostic Algorithm. Pathophysiology: 1) Represent the passage of erythrocytes from the intravascular to extravascular
Petechiae/Purpura ... - Diagnostic Algorithm ... of primary or secondary ... commonly renal and pulmonary ... Dermatology #Rash
Iron Deficiency Anemia - Differential Diagnosis Algorithm Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR • Blood loss:
Iron Deficiency Anemia ... Algorithm Labs ... extravascular) hemolysis ... athletic training, Pulmonary ... #hematology
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