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diagnosis hematology anemia blood hemolytic product vasculitis dermatologic extravascular granulomatosis hemolysis intravascular nonpalpable palpable polyangiitis taco trali transfusions vasculitides
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... vasculitis - GPA ... fever • Drug reactions ... Diagnosis #hematology ... #nonpalpable #dermatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... Maculopapular rash ... reticularis Differential ... #dermatology #rash ... #diagnosis #rheumatology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
maculopapular rash ... Purpura (PTP): ... Causes purpura & ... #diagnosis #management ... #hematology #reactions
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
maculopapular rash ... Purpura (PTP): ... Causes purpura & ... #diagnosis #management ... #hematology #reactions
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Differential Diagnosis ... prosthetic valve • Transfusion ... reactions ex. ... #classification ... #hematology
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
Reactions TRALI ... without other cause ... #Reactions #hematology ... #diagnosis #comparison ... #table
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... thrombocytopenic purpura ... reaction, Paroxysmal ... #differential # ... diagnosis #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... mucositis - Rash ... disease, drug reactions ... #diagnosis #rheumatology ... #classification
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
disease, drug reactions ... , mucositis • Rash ... MPO > PR3 60/ GPA ... tract, and often causes ... #Diagnosis #Rheumatology
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