11 results
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Leukemias Overview ... infiltrates (anemia, thrombocytopenia ... or functional neutropenia ... (CLL) and/or Small ... #Hematology #Oncology
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm
Sequestration:
 • Splenomegaly
Marrow Infiltration:
 • Hematologic and non-hematologic
Causes of Neutropenia ... with Pancytopenia ... Myelofibrosis Stem cell ... #Diagnosis #Algorithm ... #Causes #Hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Cytopenias: • Neutropenia ... , anemia, thrombocytopenia ... leukemia #CLL ... #diagnosis #workup ... #oncology #hematology
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
infections from neutropenia ... Diagnosis: • Pancytopenia ... Consider stem cell ... antibiotics if neutropenic ... to MDS or acute leukemia
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Differential Diagnosis Algorithm ... Leukemia, Tumour ... ITP • SLE • CLL ... #Causes #Hematology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
(CLL) - Summary ... Symptoms of anemia or thrombocytopenia ... PRCA, autoimmune neutropenia ... with anemia or thrombocytopenia ... #oncology #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... not required in all ... ITP, unexplained pancytopenia ... Diagnosis #Causes #Workup ... #hematology
Hematology Algorithms 

Anemia is described as a reduction in the proportion of the red blood cells.
Hematology Algorithms ... Pancytopenia is ... primarily seen as neutropenia ... The etiology of pancytopenia ... #Mentzerindex #Pancytopenia
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
bone marrow + pancytopenia ... Difficulty breathing • Neutropenia ... infections/fevers • Thrombocytopenia ... virus (EBV) • Leukemia ... • Peripheral Pancytopenia
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Differential Diagnosis Algorithm ... Consider sickle cell ... Schistocytes, thrombocytopenia ... Differential #Diagnosis #Algorithm ... #workup #hematology