8 results
Practical Approach to Grading Diastolic Dysfunction

#Diagnosis #Cardiology #Diastolic #Diastology #Dysfunction #Grading #Classification #Grades #Criteria #Algorithm #Assessment
Practical Approach to Grading ... Diastolic Dysfunction ... #Grading #Classification ... #Grades #Criteria ... #Algorithm #Assessment
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
cellular antigen, leading ... to complement activation ... Complement activation ... #Classification ... #Pathophysiology
Pathogenesis of Rheumatic Fever

Pathogenesis of rheumatic fever. 
1. GAS pharyngitis leads to antigenic presentation of pathogenic
gets activated leading ... to the development ... by endothelial activation ... Exposure of Type-IV ... Rheumatic #Fever #Pathophysiology
Hypersensitivity: Definitions
 • Type I - Production of lgE Abs that bind to harmless allergens and
Definitions • Type ... degranulation, leading ... allergen causes development ... because T-Cell activation ... #Classification
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation ... IL-1 and IL-6, leading ... Presentation: • Rapid development ... nervous system (CNS) dysfunction ... Histopathologic criteria
Hepatorenal Syndrome (HRS)

Definition:
• Functional, potentially reversible kidney impairment.
• Occurs in advanced liver disease: cirrhosis, severe alcoholic
Pathophysiology: ... sympathetic + ADH activation ... Diagnosis (Clinical Criteria ... Classification: ... HRS-AKI (formerly Type
IGG-4 RELATED DISEASE

WHAT?
 • A chronic, immune-mediated fibroinflammatory disease with tumefactive infiltration of IgG4+ plasma cells
- Organ dysfunction ... PATHOPHYSIOLOGY ... • Pancreas: Type ... • Essential Criteria ... complement • Classification
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
cytopenias and organ dysfunction ... Types of HLH • ... Pathophysiology ... Diagnostic Criteria ... of 8 HLH-2004 criteria