7 results
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
, seasonal hay fever ... cellular antigen, leading ... Complement activation ... #Classification ... #Pathophysiology
Pathogenesis of Rheumatic Fever

Pathogenesis of rheumatic fever. 
1. GAS pharyngitis leads to antigenic presentation of pathogenic
Pathogenesis of Rheumatic Fever ... to the development ... by endothelial activation ... Exposure of Type-IV ... #Pathophysiology
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Summary table of types ... Anaphylaxis, Hay fever ... cell antigens, leading ... to complement activation ... allergy #table #classification
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation ... IL-1 and IL-6, leading ... Presentation: • Rapid development ... Histopathologic criteria ... MAS #Macrophage #Activation
Hypersensitivity: Definitions
 • Type I - Production of lgE Abs that bind to harmless allergens and
Definitions • Type ... degranulation, leading ... allergen causes development ... because T-Cell activation ... #Classification
Hepatorenal Syndrome (HRS)

Definition:
• Functional, potentially reversible kidney impairment.
• Occurs in advanced liver disease: cirrhosis, severe alcoholic
Pathophysiology: ... sympathetic + ADH activation ... Diagnosis (Clinical Criteria ... Classification: ... HRS-AKI (formerly Type
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
Types of HLH • ... Pathophysiology ... Diagnostic Criteria ... of 8 HLH-2004 criteria ... Fever b.