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Evaluating a Patient with Presumed Cushing Syndrome #Cushings #Syndrome #Disease #Algorithm #Workup #Dexamethasone #Suppression #Test #diagnosis
Presumed Cushing Syndrome ... #Cushings #Syndrome ... Algorithm #Workup #Dexamethasone
Cushing Syndrome Testing Algorithm INDICATIONS FOR TESTING: • Suspected Cushing syndrome (central obesity, muscle weakness, refractory hypertension) Testing:
Cushing Syndrome ... Suspected Cushing syndrome ... Saliva • Low dose dexamethasone ... protocol: - 1 mg dexamethasone ... ARUPLabs #Cushing #Syndrome
Adrenal Incidentalomas: Hormone Evaluation • Zona Glomerulosa: Primary Hyperaldosteronism? - Aldosterone and renin
Fasciculata: Cushing Syndrome ... 1 mg overnight dexamethasone
Malignant Adrenal Mass - Differential Diagnosis Algorithm Suggestive of Malignancy: Inhomogenous Density, Delay in CT Contrast Washout
Polycystic Ovarian Syndrome ... Carcinoma (Positive Dexamethasone
Causes of Secondary Hypertension - Differential Diagnosis and Screening Testing Common causes: • Renal parenchymal disease
• Cushing’s syndrome ... Overnight 1-mg dexamethasone ... Mineralocorticoid excess syndromes
Bioequivalence of Corticosteroid Doses - Dexamethasone Conversion Dexamethasone 1mg Betamethasone 1mg Prednisolone 7mg Hydrocortisone 30mg Triamcinolone 5mg Methylprednisolone 5mg Dr. Keith Siau @drkeithsiau #Bioequivalence
Corticosteroid Doses - Dexamethasone ... Conversion Dexamethasone ... 1mg Betamethasone ... #pharmacology #Dexamethasone
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... • Steroids: IV Dexamethasone ... Differentiation #Syndrome
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... etoposide and dexamethasone
Cushing's Syndrome - Hypercortisolism - Diagnosis and Clinical Features 1) Skin • Thin, easily bruisable skin with
Cushing's Syndrome ... following a low-dose dexamethasone ... #Cushings #Syndrome
Spinal Cord Injury Syndromes Complete, Incomplete, Paraplegia, Tetraplegia Incomplete Spinal Cord Syndromes: - Brown Sequard Syndrome - Anterior
Spinal Cord Injury Syndromes ... Brown Sequard Syndrome ... Anterior Cord Syndrome ... Posterior Cord Syndrome ... - Central Cord Syndrome
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