18 results
Adult-Onset Still's Disease (AOSD)
Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Adult-Onset Still's ... Disease (AOSD) ... : high fever, CRP ... #Disease #AOSD ... #rheumatology #diagnosis
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
triad: Fever, Arthralgia ... Complications: MAS ... hepatitis • Pulmonary ... #Disease #diagnosis ... #management #treatment
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
Adult Onset Still's ... extremities during febrile ... Treatment - Mild ... #disease #AOSD ... #diagnosis #rheumatology
Vesiculobullous Rashes - THE ALGORITHMIC APPROACH 
Vesiculobullous rashes provoke significant angst
in many physicians (Figure 5, page
Vesiculobullous Rashes - THE ALGORITHMIC ... vesiculobullous rash and a fever ... hand-foot-and-mouth disease ... localized lesions and fever ... #Diagnosis #Dermatology
Erythematous Rashes - THE ALGORITHMIC APPROACH

Characterized by diffuse redness of the skin due to
capillary congestion, erythematous
Erythematous Rashes - THE ALGORITHMIC ... includes Kawasaki disease ... Nikolsky sign may ... #Diagnosis #Dermatology ... #Nikolsky #Febrile
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
• Adult-onset Still ... erythematosus [SLE], AOSD ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis ... #Management #Hematology
Petechial/Purpuric Rashes- THE ALGORITHMIC APPROACH 

These rashes can be especially challenging and are
associated with devastating differential
in vasculitic diseases ... petechiae/purpura with fever ... petechiae/purpura with fever ... the patient is afebrile ... #Diagnosis #Dermatology
Oroya Fever
Hematologic disease caused by Bartonella bacilliformis
Restricted to the Andes highlands of Peru & Ecuador
B. bacilliformis:
Oroya Fever Hematologic ... disease caused ... , malaise, chills ... jaundice ​• Neuro: AMS ... TREATMENT: ​• Acute
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Syndrome Acute febrile ... with systemic disease ... , breast CA - Hematologic ... Treatment: - Systemic ... Sweet #Syndrome #diagnosis
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
respiratory symptoms • Fever ... , cough, chills, ... infection • Cough, fever ... , chills, muscle ... • Isolated fever