10 results
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
Risk factors: Critical ... blood donor • Pathophysiology ... sequestration and activation ... transfusion • Pathophysiology ... #diagnosis #comparison
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... →Activation of CD8 ... accumulation of clinical ... #management #treatment ... #summary #rheumatology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
♀, ↑Age, ESRD Pathophysiology ... complex → plt activation ... : • Clinical Suspicion ... non-heparin A/C if clinical ... #Hematology #HemeOnc
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Disease, PRES Pathophysiology ... Lumbar Puncture, EEG ... CNS #neurology #rheumatology ... #management #treatment
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation ... Histopathologic criteria ... #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... : months - Criteria ... : El Escorial criteria ... EMG: LMN Signs in ... #management
Scleroderma Renal Crisis (SRC)

Clinical Presentation of Scleroderma Renal Crisis:
1) Acute kidney injury
2) Abrupt onset of hypertension
3)
Crisis (SRC) Clinical ... anemia (MAHA) Pathophysiology ... endothelial cell activation ... Renal #Crisis #rheumatology ... #management
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
diagnosis but rather ... ECG is vital while ... establishing a diagnosis ... #algorithm #management ... #cardiology #treatment
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... • Excessive activation ... Transverse Myelitis - Clinical ... Criteria: • Sensory ... #management #neurology
Preoperative Risk Evaluation

Major Pre-Op Questions:
1. Does the patient have any modifiable risk factors that could be
event, follow ACC algorithm ... Change in clinical ... one post op Cardiology ... medical and surgical management ... stratification #diagnosis