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management neurology signs sle complications rheumatology syndrome agraphia alexia barre clinical comparison crisis differential druginduced encephalopathy erythematosus gbs guillain manifestations
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... Myopathy (Also caused ... Complications #pathophysiology ... #signs #symptoms ... #diagnosis
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms ... CRP - Usually normal ... Discontinuation of causal ... sle #comparison #table ... #rheumatology #diagnosis
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... hair follicles -> causes ... Manifestations #pathophysiology ... #diagnosis #signs ... #symptoms #complications
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Sarcoidosis - Diagnosis ... survival is 93-95% Pathophysiology ... are not caused ... skin (16-32%): lupus ... ), liver (pain/abnormal
Alexia Without Agraphia Alexia without agraphia is a disconnection syndrome where patients cannot read but can write.
the most common cause ... production of oral ... Pathophysiology: ... Agraphia #clinical #neurology ... #diagnosis #pathophysiology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Etiology: • Pathophysiology ... Neurological symptoms ... the underlying cause ... until cause identified ... #management #neurology
Guillain-Barré Syndrome (GBS) Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness Epidemiology: • Incidence: 1
Incidence: 1 to 2 cases ... protein with a normal ... - Of note, normal ... than one after symptom ... the underlying pathophysiology
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... Bilateral signs and/or symptoms ... Sjogren's • CSF: - Abnormal ... • Infectious causes ... #management #neurology
Scleroderma Renal Crisis (SRC) Clinical Presentation of Scleroderma Renal Crisis: 1) Acute kidney injury 2) Abrupt onset of hypertension 3)
hypertension 3) Abnormal ... anemia (MAHA) Pathophysiology ... , add other BP meds ... • Refractory cases ... #rheumatology #nephrology
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