21 results
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Erythematosus (SLE) - Diagnosis ... • Immunologic Workup ... Positive in 60-80% of cases ... life-threatening • Treatment ... #rheumatology
Cardiac Tamponade - Guidelines for Crises in Anaesthesia
Caused by an accumulation of blood, pus, effusion fluid
thoracotomy is a better treatment ... Plan definitive management ... Intraoperative #Checklist ... #Diagnosis #Management ... #Workup
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
Treatment depends ... maintained fever CAUSES ... Anesthesiology #Anesthesia #Checklist ... #Diagnosis #Management ... #Workup
Intraoperative Sepsis - Guidelines for Crises in Anaesthesia

Severe sepsis (hypotension persisting after initial fluid challenge of
within 1 h (seek microbiology ... Discuss ongoing management ... Intraoperative #Checklist ... #Diagnosis #Management ... #Workup
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
and Management ... normal in mild cases ... Avoid meds that ... #Management #treatment ... #hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Disease, PRES Pathophysiology ... autoantibodies that will cause ... permeability Diagnosis ... #cerebritis #diagnosis ... #management #treatment
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... • Immunologic Workup ... life-threatening • Treatment ... Usual therapeutic management ... #diagnosis #management
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... Lysis Syndrome: • Pathophysiology ... Syndrome #TLS #diagnosis ... #management #hematology
Intraoperative Anaphylaxis - Guidelines for Crises in Anaesthesia
• Unexplained hypotension
• Unexplained bronchospasm (wheeze may be absent
trolley, anaphylaxis treatment ... require prolonged treatment ... Intraoperative #Checklist ... #Diagnosis #Management ... #Workup
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... Drugs, Unknown cause ... Treatment: • ... #management #treatment ... #summary #rheumatology