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differential management oncology erythematosus hemolytic hepatology hepatopulmonary lactate lupus sle systemic treatment typea typeb agglutinin aplastic canimorsus capnocytophaga cerebritis champs
Lactic Acidosis - Classification and Differential Diagnosis Type A Lactic Acidosis: Inadequate Oxygen Delivery • Anaerobic muscular
Lactic Acidosis ... Type A Lactic Acidosis ... Type B Lactic Acidosis ... with underlying disease ... #Acidosis #Classification
Lactic Acidosis - Overview and Pathophysiology Lactic acid is an endogenous substrate for gluconeogenesis, that is constantly
Lactic Acidosis ... of underlying disease ... acidosis) Lactic ... #Acidosis #types ... #classification
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
presentations and disease ... A Lactic Acidosis ... B Lactic Acidosis ... #causes #typea ... #typeb #classification
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... glomerulopathy, cirrhosis ... Chain deposition disease ... antiphospholipid syndrome ... #differential #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Extravascular Causes ... ) - HELLP syndrome ... - Drugs (Beta lactam ... #hematology #anemia
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... : • Clinical triad ... • Autoimmune diseases ... #types #classification ... #rheumatology #
Clinical Classification of Pulmonary Hypertension 1. Pulmonary arterial hypertension from pulmonary vasculopathy Idiopathic pulmonary arterial hypertension Heritable gene mutations
Clinical Classification ... Chronic hemolytic anemia ... multifactorial mechanisms Hematologic ... #Diagnosis #Differential ... #Causes
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Clinical Presentation ... and petechiae Causes ... propylthiouracil) - β-lactam ... #oncology #hematology ... #diagnosis #management
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... skin that are caused ... Out Secondary Causes ... Myeloproliferative Disease ... #diagnosis #hematology
Von Willebrand Disease Classification Type 1 (Accounts for ~3/4 of cases): • Defect: Quantitative defect (i.e. not
Von Willebrand Disease ... Classification ... Bleeding: Severe (Clinically ... #Types #diagnosis ... #hematology
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