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management differential hodgkins leukemia lymphoma acute agglutinin aplastic apml bilirubin chronic cll cold comparison congenital dermatology disease disorders erythematosus gammopathy
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation ... Syndrome in APML ... ATRA treatment Pathophysiology ... : >3 symptoms, or ... #hematology #oncology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
translocation • Types ... : Classification ... on: - Cell type ... NonHodgkins #comparison #oncology ... #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... Constitutional Syndromes ... • Improve the symptoms ... #oncology #hematology ... #diagnosis #management
Post-Transplantation Lymphoproliferative Disorders (PTLD) Definition: Lymphoid and/or plasmacytic proliferations that occur as a result of immunosuppression in
, unexplained hematologic ... extralymphatic tissues Diagnosis ... and classification ... Lymphoproliferative #Disorders #oncology ... #diagnosis #management
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... One blood cell type ... of one or more types ... #diagnosis #hematology ... #oncology
Acute Retroviral Syndrome Acute Retroviral Syndrome is the symptomatic presentation of acute human immunodeficiency virus infection •
mononucleosis/flu type ... enzymes ↑ • Mild anemia ... • HIV-1/HIV-2 differentiation ... immunoassay • If differentiation ... #HIV #diagnosis
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Agglutinin Disease 3 Types ... Cold Agglutinin Syndrome ... of anemia include ... anemia • Cold ... #hematology #diagnosis
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework Hematologic disorder characterized by the presence of either
No evidence of anemia ... constitutional symptoms ... level (non-IgM type ... insufficiency, Anemia ... #diagnosis #oncology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
development of skin symptoms ... , breast CA - Hematologic ... such as certain types ... #diagnosis #dermatology ... #oncology
Inherited Non-hemolytic Disorders of Hyperbilirubinemia == Disorders of Conjugation == Gilbert Syndrome: • 5-10% of the population
examination; nonspecific symptoms ... : • Type I CN ... type II rarely ... Congenital #bilirubin #hepatology ... #diagnosis #gastroenterology
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