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anemia causes algorithm platelet workup bleeding bruising disease hemolytic laboratory rheumatoid thrombocytopenia agglutinin ana antibodies antinuclear arthritis atlas bloodcell classification
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential ... Diagnosis and Workup ... gastric bypass), LFT ... (liver disease) ... #Workup #hematology
Anemia - Underproduction Diagnostic Algorithm - Iron deficiency anemia - Anemia of chronic inflammation - Anemia
Underproduction Diagnostic ... Probable bone marrow disorder ... - TSH, LFTs, ... Underproduction #Algorithm #hematology ... #diagnosis #differential
Approach to a Positive (+) Rheumatoid Factor (RF) (+) RF does not always = RA Rheumatic disorders: •
RA Rheumatic disorders ... of Liver & Lung ... Rheumatoid #Factor #RF #rheumatology ... #laboratory #differential ... #diagnosis
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Bleeding / Bruising - Differential ... Diagnosis Algorithm ... Sequestration Disordered ... Iatrogenic) • Liver ... #Causes #Hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Diagnosis Framework ... deficiency • Liver ... #Diagnosis #hematology ... #rheumatology #
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Volume (MCV) - Differential ... Diagnosis Algorithm ... • Small Bowel Disorder ... #Diagnosis #Algorithm ... #Causes #Hematology
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Folate deficiency, Liver ... Unstable hemoglobin disorders ... hemoglobinuria, IgM ... RBC #Morphology #differential ... #diagnosis #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Warm" (usually IgG ... lymphoproliferative disorders ... Extravascular #Causes #differential ... #diagnosis #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
lymphoproliferative disorder ... infection, autoimmune disorder ... younger pts) Differential ... IgM Includes Disorders ... hemolytic #anemia #hematology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Immunodeficiency disorder ... late adulthood • Diagnosis ... disease • Liver ... conditions Diagnosis ... hypogammaglobulinemia #immunology #hematology
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