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Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
Gitelman Syndrome ... tubule (DCT) Clinical ... ratio 0.5%) Differential ... Renal tubular acidosis ... #diagnosis #nephrology
Hypokalemia - Differential Diagnosis Algorithm Extra-renal Losses: • Normal Acid-Base: Low intake • Metabolic acidosis: Gl tract
Aldosterone: Liddle's Syndrome ... SAME, Cushing Syndrome ... diuretics, Bartter syndrome ... , Gitelman syndrom ... potassium #low #nephrology
Central Cord Syndromes - Anterior Cord Syndrome - Central Cord Syndrome - Brown Sequard Syndrome #CentralCord #Syndromes
Central Cord Syndromes ... Anterior Cord Syndrome ... - Central Cord Syndrome ... Brown Sequard Syndrome ... #Diagnosis
Glomerular Diseases - Nephritic and Nephrotic Syndromes Nephritic syndrome: - Acute poststreptococcal glomerulonephritis - Rapidly progressive
and Nephrotic Syndromes ... Nephritic syndrome ... Nephrotic syndrome ... Nephritic #Nephrotic #Syndromes ... #Diagnosis *
Inherited Colorectal Cancer (CRS) Syndromes Adenomatous Polyposis Syndromes: • Familial Adenomatous Polyposis (FAP), Attenuated FAP (AFAP), MUTYH
Colorectal Cancer (CRS) Syndromes ... Adenomatous Polyposis Syndromes ... Urinary → Lynch Syndrome ... Peutz-Jeghers Syndrome ... #diagnosis #management
Glomerular Diseases - Nephritic and Nephrotic Syndromes Nephritic syndrome—due to GBM disruption. Hypertension. t BUN and creatinine.
and Nephrotic Syndromes ... Nephritic syndrome—due ... Nephritic #Nephrotic #Syndromes ... #Proteinuria #Nephrology ... #Diagnosis
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear Visual or auditory symptoms in conjunction
BEE Syndromes - ... causes: • Susac syndrome ... disease • Cogan syndrome ... • Sjögren syndrome ... #differential #
High Anion Gap Metabolic Acidosis (HAGMA) - Differential Diagnosis - GOLDMARK Glycols - ethylene and propylene glycol Oxoproline
Gap Metabolic Acidosis ... (HAGMA) - Differential ... Diagnosis - GOLDMARK ... with short bowel syndrome ... #mnemonic #nephrology
Nephritic vs Nephrotic Syndrome Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes. Step
Nephritic vs Nephrotic Syndrome ... nephrotic/nephritic syndromes ... Nephritic #Nephrotic #Syndrome ... Comparison #Algorithm #Nephrology ... #Diagnosis
Causes of Metabolic Alkalosis - Differential Diagnosis Chloride depletion syndromes • Gastrointestinal losses -
depletion syndromes ... - Bartter syndrome ... - Gitelman syndrome ... • Liddle syndrome ... • Milk alkali syndrome
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