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management rheumatology causes differential druginduced sle activation ckd comparison dermatology emergencies erythematosus hemeonc hemodialysis macrophage mas oncologic oncology petechiae petechial
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms ... NPSLE rare, Malar rash ... in >90% - Low ... • Treatment: ... #diagnosis #management
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... Manifestations: Malar rash ... of SLE versus DIL ... 60-80% - Low ... life-threatening • Treatment
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
- Differential Diagnosis ... Algorithm Pinpoint ... fulminans - DIC ... Autoimmune Vasculitis (lupus ... #Algorithm #Causes
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
Constitutional symptoms ... NPSLE rare, Malar rash ... in >90% - Low ... #DIL #rheumatology ... #diagnosis #treatment
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
disease • Systemic lupus ... Petechial or purpuric rash ... SJIA], systemic lupus ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
- Differential Diagnosis ... : • Triad of symptoms ... urine • Other symptoms ... Monitor potassium ... #nephrology
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
syndrome): - Hematologic ... acid, high LDH, low ... high d-dimer, low ... - CRS: fever, rash ... Oncology #HemeOnc #Diagnosis
Management of Pruritus in Patients with Chronic Kidney Disease Pruritus with no primary lesions - differential diagnosis:
- differential diagnosis ... pruritus • Hematologic ... #Pruritus #Treatment ... #Algorithm #Hemodialysis ... Uremia #Management #Nephrology
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