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differential dermatology oncology syndrome aortitis approach bleeding bruising cryofibrinogenemia cryoglobulins erythematosus glomerulonephritis hypertension management monoclonal nonpalpable palpable paraproteinemias progressive pulmonaryhypertension
Clinical Classification of Pulmonary Hypertension 1. Pulmonary arterial hypertension from pulmonary vasculopathy Idiopathic pulmonary arterial hypertension Heritable gene mutations
Chronic hemolytic anemia ... Systemic disorders ... #Hypertension #PHTN ... #Diagnosis #Differential ... #Causes
Causes of Pulmonary Hypertension - Differential Diagnosis Algorithm Pulmonary Arterial Hypertension • Idiopathic • Associated with:
Causes of Pulmonary ... Algorithm Pulmonary ... Dysfunction: • Systolic ... PulmonaryHypertension #PHTN ... #Algorithm #Causes
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... • Autoimmune diseases ... lupus erythematosus ... #types #classification ... #rheumatology #
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... - Hemolytic anemia ... /HSP • Cryoglobulinemia ... (MIXED) • ANCA ... #hematology #rheumatology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... ASA) • Renal Disease ... • Steroids • Vasculitis ... #Algorithm #Causes ... #Hematology
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
- Differential Diagnosis ... Arthritis (RA), Systemic ... lupus erythematosus ... Cancer, Histiocytic disorders ... #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
often causes arthritis ... as systemic lupus ... purpura: strong sign ... #rheumatology # ... classification
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
pathophysiologic causes ... Post-strep GN, Lupus ... Nephritis, Cryoglobulinemia ... With associated pulmonary ... #algorithm #rheumatology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Chronic Bleed - Any ... Disease • Marrow ... #Classification ... #Algorithm #Causes ... #Hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Classification: ... Differential Diagnosis ... lymphopenia, low PLT • Anemia ... #Diagnosis #Rheumatology
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