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eosinophilia management algorithm allergy anemia aplastic bruising eosinophil hemostasis hes hypereosinophilia mds myelodysplasia myelodysplastic neutropenia syndromes thrombocytosis tryptase
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... • Screen for secondary ... causes of eosinophilia ... #Differential # ... diagnosis #hematology
Hypereosinophilia Syndrome (HES) - Diagnosis and Management Definition: An absolute eosinophil count (AEC) greater than 1500 and
Hypereosinophilia Syndrome ... (HES) - Diagnosis ... Secondary Causes ... #diagnosis #hematology ... #differential #
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Diagnosis Secondary ... Myelodysplastic syndrome ... Chronic myeloid leukemia ... #Diagnosis #Causes ... #hematology #secondary
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
• (Peripheral eosinophilia ... • Tumor lysis syndrome ... bone marrow and secondary ... #Hematology #Oncology ... #Diagnosis
Approach to Elevated Tryptase - Differential Diagnosis Framework The DDx of elevated tryptase can be broken down
Diagnosis Framework ... ESRD & CAD • Eosinophilic ... GI Disorders ... cell activation syndrome ... #Diagnosis #hematology
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
- Differential ... Diagnosis Neonate ... hypertension and/or drug treatment ... #diagnosis #causes ... #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... DDX: Rule Out Secondary ... blood count with differential ... #diagnosis #hematology ... #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
ecchymoses, mucosal bleeding ... and petechiae Causes ... - Hepatitis, eosinophilic ... virus (EBV) • Leukemia ... #hematology #diagnosis
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
Diagnosis Framework ... gingivitis or gingival leukemic ... von Willebrand syndrome ... discern these causes ... #Diagnosis #Hematology
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