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myelodysplastic antimda5 antimda5dm antinxp2 antinxp2dm aplastic classification dermatologic erythematosus gpa granulomatosis hodgkins leukemia lupus lymphoma manifestations mds monoclonal myelodysplasia paraproteinemias
Cutaneous manifestations associated with myelodysplastic syndrome • Myeloid hemopathy with the most frequent skin lesions (20%)
manifestations (dermatomyositis ... #differential # ... diagnosis #dermatology ... #oncology #clinical ... #skin
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
Cutaneous manifestations ... (blue-purple) rash ... auricular papules Clinical ... #rheumatology # ... dermatology #diagnosis
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Most common extra cutaneous ... Causes: - Idiopathic ... , breast CA - Hematologic ... #diagnosis #dermatology ... #oncology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... Rarely dominate the clinical ... Polyangiitis #GPA #dermatology ... #rash #diagnosis ... #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Differential ... Still disease, dermatomyositis ... lymphopenia, low PLT • Anemia ... #Rheumatology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Clinical Presentation ... Headaches • Pale skin ... and petechiae Causes ... #oncology #hematology ... #diagnosis #management
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
gangrenosum • Cutaneous ... (-) hemolytic anemia ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
in the neck Cutaneous ... Muscle atrophy may cause ... #diagnosis #management ... #rheumatology # ... dermatology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
just beneath the skin ... that are caused ... blood count with differential ... #diagnosis #hematology ... #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
- infiltrates (anemia ... violaceous, nontender cutaneous ... CLL -> Invade Skin ... #Leukemia #Hematology ... #Oncology #Diagnosis
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