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rheumatology algorithm systemic pruritus activation agglutinin antinxp2 antinxp2dm cold common cryoglobulinemia cryoglobulins cvid dermatomyositis dress erythematosus hemolytic hodgkins hyperpigmentation hypogammaglobulinemia
Disorders of Pigmentations - Hypopigmentation and Hyperpigmentation - Differential Diagnosis Algorithm HYPOPIGMENTATION Diffuse Congenital - Generalized hypopigmentation of
Diffuse Congenital - Generalized ... • Addison's disease ... McCune Albright syndrome ... #skin #dermatology ... #causes
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Pruritus - Generalized ... Differential Diagnosis ... Myelodisplastic syndrome ... Pruritus #primary #secondary ... #dermatology #Differential
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... purple, hemorrhagic skin ... - Hemolytic anemia ... #Diagnosis #hematology ... #nonpalpable #dermatology
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Pruritus - No Primary Skin ... Myelodisplastic syndrome ... #systemic #generalized ... #dermatology #Differential ... #causes
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Agglutinin Syndrome ... Viral Infection Clinical ... presentation) • Cutaneous ... younger pts) Differential ... #hematology #diagnosis
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Definition: • Severe adverse drug reaction, characterized by
rash in association ... Resolution > 15 days Differentials ... SJS/TEN • Acute Generalized ... SinaiBmoreIMRes #DRESS #Syndrome ... #dermatology #diagnosis
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
with systemic disease ... Rare Disorder: ... Causes: - Idiopathic ... #diagnosis #dermatology ... #oncology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... 3rd Decade Skin ... Disease Classification ... permanent alopecia Differential ... lymphopenia, low PLT • Anemia
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
: • Clinical triad ... • Autoimmune diseases ... Type III Often Secondary ... Henoch-Schönlein purpura) • Cutaneous ... #types #classification
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Immunodeficiency disorder ... infection risk secondary ... to 8 years Clinical ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
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