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hematology management differential neurology signs syndrome monoclonal infections infectiousdiseases leukemia mgus workup algorithm causes chronic gammopathy hodgkins immunology lymphocytic lymphoma
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
ALL Symptoms: ... extramedullary disease ... - infiltrates (anemia ... ) CLL Symptoms: ... #Oncology #Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... with no early symptoms ... cells can indicate disease ... • Neutropenia, anemia ... #workup #oncology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
• Clinical features ... Differential Diagnosis ... NonHodgkins #comparison #oncology ... #diagnosis #differential ... #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Lymphocytic Leukemia (CLL ... immunophenotype Clinical ... chemotherapy for low-risk disease ... uw_IMresidency #CLL ... Lymphocytic #Leukemia #oncology
Multiple Myeloma and Monoclonal Gammopathies C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN R
ULN R - Renal disease ... 40 ml/min A - Anemia ... diseases, CML, ... Gammopathies #MGUS #diagnosis ... #hematology #oncology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Viral Infection Clinical ... of anemia include ... anemia • Cold ... malignancies -> CLL ... #hematology #diagnosis
Multiple Myeloma Diagnosis and Management Summary Clinical Signs: • hyperCalcemia 28% (bone demineralization) • Renal disease 48%
Management Summary Clinical ... demineralization) • Renal disease ... hypercalcemia) • Anemia ... plasma clonal cell ... #Management #oncology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Lymphoma (HCV) • CLL ... • Heavy Chain disease ... (-) hemolytic anemia ... #Differential #Diagnosis ... #Oncology
Krabbe Disease Check out this interesting case of Krabbe disease, a rare genetic leukodystrophy. Diagnosis was
Krabbe Disease ... Diagnosis was made ... neurotoxic • Symptoms ... Symmetric abnormal WM ... #Diagnosis #MRI
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis Neurologic-Centered: (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Gammopathy of Clinical ... - Differential Diagnosis ... Ig deposition disease ... ) Ig deposits: TMA ... #hematology #oncology
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