10 results
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Gitelman Syndrome ... Family history of hypokalemia ... • Unexplained hypokalemia ... #Syndrome #diagnosis ... #nephrology #management
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
Hypokalemia Evaluation ... Before evaluating hypokalemia ... in evaluating hypokalemia ... , Gitelman syndrome ... #nephrology #low
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
Metabolic Alkalosis ... alkalosisKidney ... diuretic use, Bartter syndrome ... , Gitelman syndrome ... urine #Algorithm #nephrology
Gitelman Syndrome - Diagnosis and Workup
Blood Work:
 - Hypokalemia
 - Hypomagnesemia
 - Metabolic Alkalosis
 - Elevated
Gitelman Syndrome ... Blood Work: - Hypokalemia ... Alkalosis - Elevated ... #Syndrome #Diagnosis ... #Workup #nephrology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
- Compartment syndrome ... Neuroleptic malignant syndrome ... • LDH ↑ • Hyperkalemia ... or compartment syndrome ... #treatment #nephrology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... Suspicion for Hyperkalemia ... - Tumor lysis syndrome ... #causes #potassium ... #high #nephrology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... Suspicion for Hyperkalemia ... - Tumor lysis syndrome ... #causes #potassium ... #high #nephrology
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
iniury, Compartment syndrome ... /training, Seizures ... Neuroleptic malignant syndrome ... Monitor potassium ... Dialysis for severe hyperkalemia
Rhabdomyolysis - Differential Diagnosis Framework
Rhabdomyolysis = Destruction of skeletal muscle with leakage of contents into circulation.
Strenuous exercise, Seizures ... Neuroleptic malignant syndrome ... Electrolytes: Hypokalemia ... #Causes #nephrology ... #table
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
disequilibrium syndrome ... and nephrotic syndrome ... and nephrotic syndrome ... disease • Liddle syndrome ... #Diuresis #Nephrology