19 results
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
Autoantibodies and their Disease ... syndrome Anti-Scl ... (TTG) - Celiac disease ... #diagnosis #table ... #rheumatology #
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Syndrome Systemic disease ... aseptic meningitis), MCC ... : Arterial (MCC-small ... Arthritis, AS Treatment ... signs #symptoms #rheumatology
Optic Neuritis - Diagnosis and Management
 • Epidemiology: Female (75%), 18-50 years,
caucasian
 • Symptoms: Moderate visual
lesions (b) • CSF Analysis ... corticosteroids TREATMENT ... other auto-immune diseases ... Diagnosis #Management #treatment ... #rheumatology #
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Autoimmune diseases ... Adult-onset Still disease ... Unknown cause Treatment ... diagnosis #management #treatment ... #summary #rheumatology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
intracranial pressure • Dialysis ... Inhibitors of Na+K+2Cl ... chronic kidney disease ... Tolvaptan) • Treatment ... #Medications #Table
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Treatment of underlying ... disease 2. ... urine output: 200 ml ... per day until stable ... Dialysis for severe
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
highly inflammatory disease ... of underlying disease ... 5000 to 10,000 ng/mL ... Treatment: • Corticosteroids ... #Rheumatology
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
Onset Still's Disease ... Ferritin >3000 ng/mL ... Treatment - Mild ... : NSAIDS Treatment ... AOSD #diagnosis #rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
constitutional symptoms • Treatment ... life-threatening • Treatment ... Evolution: Chronic disease ... sle #comparison #table ... #rheumatology #
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
age, however the disease ... Ferritin >500 ng/mL ... • Bicytopenia Treatment ... diagnosis #management #treatment ... #hematology