15 results
Hypersensitivity: Definitions
 • Type I - Production of lgE Abs that bind to harmless allergens and
cell surfaces causes ... allergic reaction ... causes development ... An allergic reaction ... #Allergic #Reactions
Type I Hypersensitivity: Pathogenesis and clinical findings
Definition: Production of lgE Antibodies that bind to harmless allergens
degranulation, leading ... to an allergic ... reaction. ... Sensitization" to Allergen ... #Immunology #pathophysiology
Type IV Hypersensitivity: Pathogenesis and clinical findings
Definition: Unique because it is entirely T-Cell mediated; exposure to
mediated; exposure to allergen ... causes development ... of allergen-specific ... Allergic reaction ... #Immunology #pathophysiology
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Mechanism of Action: Allergen-specific ... lgE causes mast-cell ... cell antigens, leading ... glomerulonephritis, Systemic lupus ... #types #allergy
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
When the specific allergen ... cellular antigen, leading ... , and systemic lupus ... Classification #Pathophysiology ... #Reactions #Table
Type III Hypersensitivity: Pathogenesis and clinical findings
Definition: Small antigen-antibody complexes (produced from normal immune response to
self-antigens are the cause ... : • Systemic Lupus ... antigens are the cause ... HypersensitivityReaction #Allergy ... #Immunology #pathophysiology
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... Myopathy (Also caused ... #Systemic #Lupus ... Erythematosus #SLE #MSK ... Complications #pathophysiology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic Lupus ... Disease, PRES Pathophysiology ... autoantibodies that will cause ... inflammation, leading ... Diagnosis of Lupus
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect
Examples: Valproate, Carbamazepine, Lamotrigine
 • Mild anticholinergic effect -> Drowsiness
constipation • Allergic ... reaction -> Benign ... mediated cytotoxic reaction ... Systemic effect -> Nausea ... #SideEffects #Pathophysiology
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Allergic reaction ... Causes purpura & ... Injury (TRALI): Leading ... cause of transfusion ... more likely to cause