6 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
of Systemic Lupus ... Disease, PRES Pathophysiology ... autoantibodies that will cause ... #Lupus #Erythematosus ... #SLE #CNS #neurology
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... Myopathy (Also caused ... #Lupus #Erythematosus ... #SLE #MSK #Musculoskeletal ... Complications #pathophysiology
Type III Hypersensitivity: Pathogenesis and clinical findings
Definition: Small antigen-antibody complexes (produced from normal immune response to
: • Systemic Lupus ... • Erythematosus ... (SLE) If bacterial ... HypersensitivityReaction #Allergy ... #Immunology #pathophysiology
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
- Local and systemic ... cellular antigen, leading ... arthritis, and systemic ... lupus erythematosus ... Classification #Pathophysiology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
IL-1 and IL-6, leading ... lupus erythematosus ... (CNS) dysfunction ... lupus erythematosus ... [SLE], AOSD) •
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
lgE causes mast-cell ... cell antigens, leading ... glomerulonephritis, Systemic ... lupus erythematosus ... T-cells recruit macrophages