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diagnosis hematology differential causes abnormal aptt dic disseminated intravascular prolonged ptt heparin laboratory management pathophysiology thrombin warfarin aafp anticoagulant anticoagulation
Coagulation cascade and anticoagulants Satyendra Dhar MD, @DharSaty #coagulation #coumadin #heparin #warfarin #apaxiban #pradaxa #xarelto #DOAC #vWF
Coagulation cascade ... @DharSaty #coagulation ... thrombin #ptt #pt
Coagulation Cascade Mnemonic - PITT vs PET PITT (with an I) = Intrinsic = APTT
Coagulation Cascade ... E)= Extrinsic=PT ... @pinoygastro #Coagulation ... #Cascade #Mnemonic
Coagulation Protein Tests (PT and PTT) #Coagulation #Tests #PTT #algorithm #differential #pathophysiology
Coagulation Protein ... Tests (PT and PTT ... ) #Coagulation ... #Tests #PTT #algorithm
Algorithm for Investigation of Abnormal Coagulation Tests - Prolonged PT - Prolonged aPTT and Prolonged PT - Prolonged aPTT Dr.
Algorithm for Investigation ... of Abnormal Coagulation ... Tests - Prolonged PT ... and Prolonged PT ... #Coagulation #Abnormal
Causes of Prolonged PT (INR), Prolonged PTT • Prolonged PT (INR), Prolonged PTT • Prolonged PT
Causes of Prolonged PT ... • Prolonged PT ... • Prolonged PT ... Differential #Diagnosis #Algorithm ... Causes #Hematology #coagulation
ISTH Scoring System for Disseminated Intravascular Coagulation (DIC) Platelet count: • Expected: Low (or normal) • Elevation
Intravascular Coagulation ... (DIC) Platelet ... platelet aggregation PT ... consumption of coagulation ... using INR use PT
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
The coagulation ... cascade is shown ... #Coagulation #Cascade ... thrombin #clot #PT
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Intravascular Coagulation ... (DIC) Overview ... • Prolonged PT ... is simultaneous coagulation ... Fibrinogen: ↓ • PT
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal PT ... Congenital intrinsic coagulation ... intravascular coagulation ... (DIC) c. ... differential #hematology #coagulation
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
inhibitor of a coagulation ... integrity Clotting cascade ... Warfarin • Acute DIC ... intravascular coagulation ... disease • Acute DIC
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