12 results
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
tuberculosis (LTBI) Pathophysiology ... affecting the lungs ... lymph nodes Risk ... • Progressive lung ... Inhibitor: • Risk
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
tuberculosis (LTBI) Pathophysiology ... affecting the lungs ... lymph nodes Risk ... • Progressive lung ... Inhibitor: • Risk
Nontuberculous Mycobacteria (NTM) Infections 

Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
Food products Risk ... Illnesses: • Pulmonary ... complicate MAC pulmonary ... infiltrates NTM Pulmonary ... #differential #
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
polymicrobial infection ... pneumonia • DM risk ... Abscess Pathophysiology ... #Abscess #pulmonary ... #differential #
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
MUCORMYCOSIS • Risk ... Encapsulated yeast • At risk ... Aspergillosis Pathophysiology ... change in the lungs ... nails, bronchi, lungs
Lung Infections in HIV - Differential Diagnosis Framework

Disease by CD4 Count:
Any CD4 Count:
 • Mycobacterium tuberculosis,
Lung Infections ... in HIV - Differential ... Pneumonia: • Risk ... #AIDS #pulmonary ... #differential #
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
ATRA treatment Pathophysiology ... Attempt if high risk ... Imaging: CXR- pulmonary ... initiation • Differential ... Diagnosis: Infection
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan
Beta-D-Glucan:
 • Polysaccharide cell wall component of many fungi
 • Pathogens:
invasive fungal infection ... surfaces - Infections ... useful in high risk ... BAL GM does not differentiate ... admin of mold-active
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... fibromyalgia) • Infections ... extremity edema, active ... Thrombosis highest risk ... and leukemia • Lung
Fluid Responsiveness and Fluid Tolerance Testing - OnePager Summary
Fluid resuscitation can be beneficial when required or
vasopressors and lower risk ... Pulmonary Artery ... via cold saline injection ... • PULMONARY A ... testing #diagnosis #criticalcare