17 results
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
crises”. ... immunologic assay - MuSK ... Crises - Severe ... Gravis #diagnosis #management ... #neurology
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
Causes of Knee Effusions ... Seronegative Reactive Syndrome ... fracture - Patellar dislocation ... #Effusions #causes ... differential #diagnosis #msk
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Causes of Neuromuscular ... Demyelinating Disease (MS ... Guillain-Barre syndrome ... , Myasthenia Gravis ... differential #diagnosis #neurology
Guillain–Barré syndrome (GBS)
(aka: Landry–Guillain–Barré–Strohl syndrome:
	Most common cause of acute flaccid paralysis
	Rapidly progressive ascending paralysis & areflexia
	Autonomic
Guillain–Barré syndrome ... Landry–Guillain–Barré–Strohl syndrome ...  Most common cause ... albumin-cytologic dissociation ... diagnosis:  Myasthenia
Myasthenia Gravis - Summary
 • an autoimmune disease of the postsynaptic neuromuscular junction associated with antibodies
antibodies - MuSK-positive ... likely to cause ... glucocorticoids - can cause ... Gravis #diagnosis #management ... #neurology #treatment
Trendelenburg Gait: Pathogenesis and clinical findings

Skeletal Pathology of the Hip
 • Arthritis
 • Congenital hip dysplasia
Chondrodysplasia Neurologic ... Fracture • Hip dislocation ... Valgus position of knee ... pathophysiology #causes ... signs #diagnosis #msk
BEE Syndromes - Non-inflammatory Causes

Immune-mediated conditions affecting the Brain, Eye, and Ear

Visual or auditory symptoms in
Non-inflammatory Causes ... Non-inflammatory causes ... neuropathy (LHON) plus MRI ... consistent with MS ... #neurology #noninflammatory
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Epidemiology: • 1-2 cases ... Albuminocytologic dissociation ... axonal form • MRI ... #diagnosis #management ... #treatment #neurology
Posterior Knee Dislocation Injury
Specifically, POSTERIOR KNEE DISLOCATIONS can have significant associated injury that needs unique approach
Posterior Knee Dislocation ... : ~25% cases. ... Neurologic deficit ... Neurologic injuries ... #Injury #msk #clinical
Bone Deformity / Limp - Differential Diagnosis Algorithm 
Infection
 • Septic Arthritis
 • Cortical Hypertrophy
 •
Arthritis Other Causes ... Legg-Calve-Perthes Disease Knee ... Patellofemoral Syndrome ... Tendon Rupture, Dislocation ... Deformity #Limp #MSK