26 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... Cerebrovascular Disease ... autoantibodies that will cause ... Lupus Cerebritis Induction ... Erythematosus #SLE
Angioedema - Classification Diagnosis and Treatment
Types of Angioedema:
 • Acute allergic angioedema - Usually occurs with
Angioedema - Classification ... Non-allergic drug reaction ... dominant inherited disease ... dominant inherited disease ... cell-mediated in > 90% of cases
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
Decreased RBC Production ... Anemia of Chronic Disease ... Non-lmmune #Anemia #Classification ... Diagnosis #Algorithm #Causes ... #Hematology
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
Causes of Knee Effusions ... arthritis - SLE ... fracture - Patellar dislocation ... Effusions: - Hematologic ... Knee #Effusions #causes
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Erythematosus (SLE ... Positive in 60-80% of cases ... life-threatening • Treatment ... Evolution: Chronic disease ... Management #Summary #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
blood cells + production ... • Autoimmune diseases ... : SLE+++, Adult-onset ... Still disease, ... Treatment: •
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
constitutional symptoms • Treatment ... Discontinuation of causal ... life-threatening • Treatment ... Evolution: Chronic disease ... comparison #table #rheumatology
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
Edema in 70% of cases ... withdrawal • Mild disease ... : symptomatic treatment ... • Severe disease ... DRESS #Syndrome #dermatology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
again we might see ... presentations and disease ... perfusion - shock->treatments ... before beginning treatment ... #typea #typeb #classification
In order to better classify heart failure, the American College of Cardiology Foundation and the American
of the ACC/AHA Classification ... Below one can see ... With treatment, ... structural heart disease ... #Stages #Classes