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diagnosis management differential anemia blood dermatology intravascular oncology product purpura reactions aplastic atlas bariatric bruising coagulation complications extravascular gastric gastroenterology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... anemia): - Disseminated ... intravascular coagulation (DIC ... Drugs (Beta lactam antibiotics ... differential #diagnosis #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
/TTP/HUS - Hemolytic ... SLE) - Viral infections ... Kasabach-Merritt syndrome ... Differential #Diagnosis #hematology ... #rheumatology #
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
• Burr cells - Renal ... uremic syndrome ... thrombocytopenia (ITP), Disseminated ... coagulopathy (DIC ... #differential #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Disseminated Intravascular ... Treat primary cause ... #Disseminated # ... #treatment #management ... #hematology
Causes of Purpura or Easy Bruising in Children Platelet count reduced, i.e. thrombocytopenia - Increased platelet destruction
Causes of Purpura ... purpura - DIC ... (disseminated intravascular ... cardiopulmonary bypass ... and other severe infections
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
pain, dark urine, DIC ... , hypoTN, renal ... Causes purpura & ... Infection - Infection ... diagnosis #management #hematology
Complications after Bariatric Surgery Post Bariatric Intestinal Failure: • Severe protein malnutrition after bariatric surgery • More
Consider refeeding syndrome ... nutrients • TPN for treatment ... complication rate (i.e. infections ... causes increased ... kidney and forms renal
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
pain, dark urine, DIC ... , hypoTN, renal ... Causes purpura & ... • Infection - ... diagnosis #management #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... - β-lactam antibiotics ... Idiopathic • Infections ... aplastic anemia Treatment ... Anemia #oncology #hematology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Rule out other causes ... such as infectious ... and lower jaw Treatment ... with acne: antibiotics ... #Rheumatology #
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