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differential hematology management ai algorithm anemia blood endocrinology insufficiency mds myelodysplastic product reactions aids apml cardiology classification dermatology differentiation endocarditis
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
anemia): - Disseminated ... intravascular coagulation (DIC ... ) - HELLP syndrome ... uremic syndrome ... Drugs (Beta lactam antibiotics
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Megakaryopoiesis • Aplastic ... Non-lmmune: • HELLP Syndrome ... • TTP/HUS • DIC ... Vasculitis • Infection ... #Hematology
Causes of Adrenal Insufficiency - Differential Diagnosis Algorithm ACTH-Dependent (Secondary): • Pituitary Dysfunction • Hypothalamic Dysfunction ACTH-Independent (Primary):
Causes of Adrenal ... Polyglandular Autoimmune Syndrome ... • Infectious: ... TB, Disseminated ... Fungal, HIV/AIDS
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... Constitutional Syndromes ... marrow-failure syndromes ... myelodysplastic syndrome ... #hematology #diagnosis
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... dys- (abnormal) -plastic ... risk-stratification • Risks: infection ... Myelodysplastic #Syndrome ... #hematology #oncology
Infectious Causes of Adrenal Insufficiency Anatomical distribution of vessels to the adrenal makes the gland prone to
Infectious Causes ... infection or disseminated ... Waterhouse-Friderichsen syndrome ... canimorsus • Virus: HIV ... #Causes #Adrenal
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... /TTP/HUS - Hemolytic ... Kasabach-Merritt syndrome ... Gardner-Diamond syndrome ... #hematology #rheumatology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Myelodysplastic Syndromes ... • Anemia • Aplastic ... isoniazid) • Antibiotics ... #diagnosis #hematology ... #oncology
Nontuberculous Mycobacteria (NTM) Infections Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
status NTM Cause ... Lady Windermere Syndrome ... : • Syndrome of ... discomfort, • +/- Hemoptysis ... #infectiousdiseases
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
- Compartment syndrome ... Neuroleptic malignant syndrome ... - Viral (HIV, Influenza ... complication: DIC ... or compartment syndrome
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