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diagnosis anesthesiology checklist intraoperative hematology syndrome hemophagocytic lymphohistiocytosis hyperthermia lupus sle summary activation anaphylaxis antinxp2 antinxp2dm behcet behcets bradycardia capillary
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Autoimmune diseases ... Unknown cause Treatment ... Lymphohistiocytosis #diagnosis #management ... #treatment #summary ... #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Lymphohistiocytosis (HLH ... age, however the disease ... • Bicytopenia Treatment ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia If prolonged or ≥ 39 C this is a
Treatment depends ... brain injury By Association ... Anesthesiology #Anesthesia ... Checklist #Diagnosis #Management ... #Workup
Behcet's Syndrome - Treatment Ulcers: • Treatment: Topical steroids • Prevention: Colchicine • Azathioprine for refractory disease Arthritis:
Behcet's Syndrome - Treatment ... Ulcers: • Treatment ... #Syndrome #Treatment ... #management #pharmacology ... #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Treatment Primary HLH: - HLH-94 Protocol • Dexamethasone
) Treatment Primary ... or autoimmune disease ... for refractory disease ... #Treatment #management ... #hematology
Intraoperative Tachycardia - Guidelines for Crises in Anaesthesia Tachycardia in theatre is often due to inadequate depth
remember to tailor treatment ... (→ 3-8) By Association ... Anesthesiology #Anesthesia ... Checklist #Diagnosis #Management ... #Workup
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Diagnosis and Management ... • Immunologic Workup ... life-threatening • Treatment ... Evolution: Chronic disease ... #Summary #rheumatology
Intraoperative Anaphylaxis - Guidelines for Crises in Anaesthesia • Unexplained hypotension • Unexplained bronchospasm (wheeze may be absent
Cutaneous flushing in association ... trolley, anaphylaxis treatment ... require prolonged treatment ... Checklist #Diagnosis #Management ... #Workup
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
Diagnosis and Management ... screening for disease ... with established disease ... Avoid meds that ... #treatment #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
lymphohistiocytosis (HLH ... hypersensitivity syndromes • HLH ... Treatment: • Corticosteroids ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
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