28 results
Tranexamic Acid - Indications and Pharmacology
Pharmacokinetics:
 • MOA: Inhibits plasminogen activation to plasmin & inhibits fibrinolysis
Indications and Pharmacology ... Inhibits plasminogen activation ... reduces complement activation ... diarrhea & abdominal pain ... #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Activation of CD8 ... IFN-y) → Excessive activation ... Auto-amplification loop Diagnosis ... #management #treatment ... #summary #rheumatology
IDSA Recommendations for Preventing Human Papillomavirus Infections and Cervical Cancer Screening for Women with in HIV-AIDS
Recommendations
or been newly diagnosed ... following initial diagnosis ... Prevention #Treatment #management ... #opportunistic ... #pharmacology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
excessive macrophage activation ... can mimic common infections ... agent are the main ... #management #treatment ... #hematology
Flutycosine - Antibiotics Class Overview
 - 
Mechanism: 5-FC interferes with DNA and protein synthesis.  Only
B for initial management ... severe fungal infections ... ) - Main adverse ... effects = Hematologic ... #Pharmacology #Antibiotics
IDSA Recommendations for Preventing and Treating Chagas Disease (American Trypanosomiasis) in HIV-AIDS
Preventing Clinical Disease
Indication:  Individuals
ART may prevent reactivation ... Prevention #Treatment #management ... #opportunistic ... #infections #HIVAIDS ... #pharmacology
Chronic Hepatitis B - Diagnosis and Management Algorithm

• Who to treat: Essentially treat the pts with
Hepatitis B - Diagnosis ... and Management ... with chronic HBV infections ... #Management #Treatment ... #Hepatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation ... • Fever is the main ... SLE], AOSD) • Infection ... #Syndrome #Diagnosis ... #Management #Hematology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
and Management ... skin necrosis (at injection ... complex → plt activation ... Management: • ... #Hematology #HemeOnc
Rheumatoid Arthritis Summary
Overview: chronic, inflammatory symmetric polyarthritis involving small joints of hands/feet, knees, shoulders
Signs & Symptoms:
inflammatory) • joint pain ... • Ultrasound Diagnosis ... : CLINICAL DIAGNOSIS ... corticosteroid injections ... #management #rheumatology