11 results
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... - Arthralgia, Arthritis ... #SLE #MSK #Musculoskeletal ... pathophysiology #signs ... #symptoms #diagnosis
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... , macular, patchy ... Differential Diagnosis ... Induced Lupus: • Symptoms ... #Diagnosis #Rheumatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Behçet's Syndrome Systemic ... skin injury) • Neurologic ... meningitis), MCC CNS symptoms ... #management #signs ... #symptoms #rheumatology
Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
desaturation, Scotoma, Ocular ... lupus erythematosus ... Manifestations #diagnosis ... #neurology #symptoms ... #signs
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Symptoms (SX) in ... purpura: Strong sign ... ischemia • Skin: Erythematous ... • Progressive symptoms ... fluid (CSF) is abnormal
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
, neurologic, and ... signs/sx of inflammation ... 50 in GCA, but normal ... GCA #Temporal #Signs ... #Symptoms #Diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential Diagnosis ... ischemia - Skin: erythematous ... lupus erythematosus ... Symptoms (Sx) in ... purpura: strong sign
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
the lymphatic system ... Extrapulmonary: ankle arthritis ... anterior/posterior MSK ... ), liver (pain/abnormal ... #Management #Signs
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
acute pulmonary, systemic ... level • A low or normal ... the circulatory system ... osteoarticular, pulmonary, ocular ... Meningitis, septic arthritis
The Neurological Evaluation of a Comatose Patient

Definition:
 • Coma: a state of unresponsiveness; the absence of
Differential Diagnosis ... reticular activating system ... • Vestibulo-ocular ... • Examine for signs ... #PhysicalExam #neurology