27 results
Radiculopathy: Signs and Symptoms
 • Back/Neck Pain
 • Decr Range of motion
 • Abnormal posturing
 •
and Symptoms ... of motion • Abnormal ... proprioception and ... Radiculopathy #MSK ... #symptoms #pathophysiology
Stress Fracture: Pathogenesis and clinical findings
Abnormal biomechanics, Repetitive impact activities
=> Repetitive subthreshold mechanical loading
=> Bone strain
=>
: Pathogenesis and ... clinical findings Abnormal ... StressFractures #msk ... #orthopedics #pathophysiology ... #symptoms #signs
Congenital Adrenal Hyperplasia - 21-Hydroxylase Deficiency - Signs and Symptoms
 • Brain: Androgenization effects, Glucocorticoid effects,
21-Hydroxylase Deficiency ... - Signs and Symptoms ... Cardiovascular: Abnormal ... #Signs #Symptoms ... #diagnosis #endocrinology
Spondylolysis & Spondylolisthesis: Pathogenesis and Clinical Findings

Pars interarticularis stress fracture (spondylolysis) - most frequently in the
: Pathogenesis and ... vertebrae • CT - collar ... Spondylolisthesis #MSK ... #diagnosis #pathophysiology ... #signs #symptoms
Hypothyroid Myopathy
Very common (up to 80% ) in patients with hypothyroidism
Pathophysiology:
 • T4 deficiency leads to
: • T4 deficiency ... leads to abnormal ... glycolysis dependent) and ... #signs #symptoms ... #endocrinology
Xeropthalmia: Pathogenesis and Ocular Manifestations

Decr Visual pigment -> Keratinization, thickening & non-wetting of the conjunctiva
Ocular Manifestations ... Xerophthalmia - abnormal ... with vitamin A deficiency ... #Xeropthalmia #pathophysiology ... #symptoms
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
activates lipolysis Signs ... /Symptoms: • GH ... deficiency: ... acromegaly, widening of hands ... #pathophysiology
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Proximal Weakness, Normal ... demineralization, and ... Erythematosus #SLE #MSK ... Complications #pathophysiology ... #signs #symptoms
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings
Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
21-Hydroxylase Deficiency ... : Pathogenesis and ... Signs/Symptoms/Complications ... #21HydroxylaseDeficiency #21OHD #pathophysiology ... #genetics #endocrinology
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
lumbar spine Signs ... Areflexia (loss of normal ... CaudaEquina #Syndrome #MSK ... #pathophysiology ... #signs