21 results
Causes of Proximal Muscle Weakness That May Mimic Inflammatory Myopathy
 • Central or peripheral neurologic disease
Causes of Proximal ... Muscle Weakness ... Myasthenia gravis • Muscular ... mimics #diagnosis #differential ... #causes #neurology
Gowers' Sign on Physical Exam

Caused by proximal muscle weakness typically seen in muscular dystrophy

#Gowers #Sign #PhysicalExam
Gowers' Sign on ... Physical Exam Caused ... proximal muscle weakness ... #PhysicalExam #neurology ... clinical #video #pediatrics
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Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Causes of Neuromuscular ... Weakness • Spinal ... Motor Nerves: ALS ... Mitochondrial myopathy, Muscular ... #Causes #differential
Generalized Weakness - Differential Diagnosis Framework
"l feel weak":
 • Infectious: Influenza, EBV, PNA, Bacteremia, Sepsis
 •
- Differential ... Polyneuropathy, ALS ... ), NMJ disorder ... Diagnosis #causes ... #neurology
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
Weakness - Differential ... Non-neuromuscular disorder ... Lack of UMN/LMN signs ... • Inflammatory disorders ... #Differential #
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
- Causes progressive ... 4) progressive muscular ... conditions listed in differential ... Lateral #Sclerosis #neurology ... #diagnosis #management
Dysphagia - Differential Diagnosis Framework

Symptom | Diagnosis
• Solid-food dysphagia present for months to years | Mechanical
Dysphagia - Differential ... regurgitation of fluids • Muscular ... the underlying cause ... #Dysphagia #Differential ... #Diagnosis #Management
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
Spinal Cord Disorders ... - Differential ... • Symptoms and signs ... Non-compressive Spinal Cord Causes ... #differential
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
an autoimmune disorder ... life-threatening Differential ... Generalized fatigue - ALS ... Gravis #diagnosis #management ... #neurology
Major neurocognitive disorders (MNCD): Diagnosis and workup 

1) Clinical diagnosis Cognitive impairment + loss of autonomy
2)
neurocognitive disorders ... Alzheimer - 1st cause ... (parkinsonian signs ... Dementia - 2nd cause ... MNCD #Dementia #Differential