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neurology algorithm amiodarone apml causes criticalcare differentiation dili drug ecmo encephalopathy gravis hematology hepatology idiosyncratic injury liver lung myasthenia nephrology
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Idiosyncratic Drug-induced ... ongoing ↑ LFTs or symptoms ... Idiosyncratic #differential ... #Diagnosis #Management
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Rhabdomyolysis - Differential ... Diagnosis Framework ... and Management ... : • Triad of symptoms ... #Diagnosis #Management
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... endothelial damage • Induce ... : >3 symptoms, or ... initiation • Differential ... #management #hematology
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
life-threatening Differential ... Penicillamine induced ... myasthenia Diagnosis ... Myasthenia #Gravis #diagnosis ... #management #neurology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Neurological symptoms ... Reversible course Differential ... Diagnosis: • ... Seizures: Treat with AEDs ... #diagnosis #management
Amiodarone Induced Lung Toxicity Summary Who? • 5% of patients • Dose ≥ 400 mg per day How? Possible
Amiodarone Induced ... respiratory distress syndrome ... gradually with symptoms ... Improvement in symptoms ... #management #Toxicology
ECMO Troubleshooting - OnePager Summary ECMO Emergency Protocol - Team should train/practice & have necessary supplies at
drainage cannula draws ... POST-CANNULATION SYNDROME ... Troubleshooting #problems #diagnosis ... #differential # ... management #criticalcare
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