10 results
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Hypocalciuria (spot ... tubular acidosis (RTA ... Treatment - ... #Syndrome #diagnosis ... #nephrology #management
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Diagnosis Algorithm ... Extra-renal Losses ... Proximal and distal RTA ... Bartter syndrome, Gitelman ... potassium #low #nephrology
Causes of Hypokalemia - Differential Diagnosis Algorithm
Defining the cause of hypokalemia starts by measuring urinary K
- Differential Diagnosis ... starts by measuring ... • Renal tubular ... Bartter's syndrome, Gitelman's ... algorithm #causes #nephrology
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
suggests extra-renal ... Bartter syndrome, Gitelman ... , Distal RTA, DKA ... #diagnosis #Algorithm ... differential #potassium #nephrology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Rhabdomyolysis - ... Differential Diagnosis ... per day until stable ... #Differential #Diagnosis ... #nephrology
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
Differential Diagnosis ... oxidative iniury Treatment ... per day until stable ... Dialysis for severe hyperkalemia ... #Differential #Diagnosis
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Diagnosis Framework ... lysis syndrome - Rhabdomyolysis ... SLE • Type IV RTA ... #differential #diagnosis ... potassium #high #nephrology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Diagnosis Framework ... lysis syndrome - Rhabdomyolysis ... SLE • Type IV RTA ... #differential #diagnosis ... potassium #high #nephrology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Hyperkalemia - Diagnosis ... Renin/Aldosterone, RTA ... tourniquet / IVF line draw ... Elimination (see Table ... #nephrology #K
Causes of Hypokalemia
Transcellular Shifts:
 - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
plasma insulin (treatment ... Villous adenoma Renal ... diuretic use), Gitelman's ... #differential #diagnosis ... #nephrology