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differential causes management potassium algorithm classification epithelial hyperkalemia hypomagnesemia hypomg inherited k kidney low magnesium pathophysiology rhabdomyolysis syndrome tubule workup
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
Hypocalciuria (spot ... (RTA)) • Refeeding ... Rhabdomyolysis Treatment ... #Syndrome #diagnosis ... #nephrology #management
Inherited Defects in Kidney Tubule Epithelial Cells Renal glucosuria - Na+-dependent glucose cotransporter Cystinuria - Amino acid transporter Bartter
Inherited Defects ... ascending limb Gitelman ... #Kidney #Nephrology ... #Diagnosis #Differential ... #Table
Causes of Hypokalemia - Differential Diagnosis Algorithm Defining the cause of hypokalemia starts by measuring urinary K
- Differential Diagnosis ... starts by measuring ... • Renal tubular ... Bartter's syndrome, Gitelman's ... algorithm #causes #nephrology
Hypomagnesemia - Etiologies by Mechanism Decreased GI Uptake - Poor dietary intake (particularly common in alcoholics)
tubular dysfunction ... syndromes - Gitelman ... - Genetic defects ... #Differential #Diagnosis ... Low #Magnesium #Table
Causes of Hypokalemia Transcellular Shifts: - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
plasma insulin (treatment ... tubular acidosis ... diuretic use), Gitelman's ... #differential #diagnosis ... #nephrology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
- Differential Diagnosis ... tubular obstruction ... per day until stable ... #Differential #Diagnosis ... #nephrology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Hyperkalemia - Diagnosis ... Renin/Aldosterone, RTA ... tourniquet / IVF line draw ... Elimination (see Table ... #nephrology #K
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