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hematology clinical differential treatment orthopedics algorithm blood criticalcare hip knee neurology oncology ophthalmology product reactions sports test activation anemia antipsychotic
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation Syndrome ... syndromes Clinical ... ALT ↑ bilirubin level ... #Diagnosis #Management ... #Hematology #Rheumatology
Platypnea-Orthodeoxia Syndrome on Physical Exam The case of a patient with a diagnosis of cirrhosis and platypnea-orthodeoxia
Platypnea-Orthodeoxia Syndrome ... patient with a diagnosis ... addition, there is a drop ... #PhysicalExam # ... clinical #video
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 Shock - Differential Diagnosis Framework - MAP <65. SBP <90, drop in SBP > 40 -
- Differential Diagnosis ... SBP <90, drop in ... Insufficiency, Liver ... Abdominal compartment syndrome ... algorithm #treatment #management
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Sarcoidosis - Diagnosis ... and Management ... at the time of diagnosis ... anterior/posterior MSK ... #Management #Signs
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... following: • Fever ... lymph node, or liver ... #management #treatment ... #hematology
Causes of Knee Effusions - Differential Diagnosis Framework Knee Effusion Red Flags: 1. Fever/Chills/Joint pain/Night sweats/Weight loss - DDX: -
- Differential Diagnosis ... Osteoarthritis - Overuse syndrome ... Seronegative Reactive Syndrome ... #differential #diagnosis ... #msk #physicalexam
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Low serum IgG level ... and M panel Management ... : • Nephrotic syndrome ... (Epstein-Barr syndrome ... #diagnosis #management
Leg Pain - Differential Diagnosis Framework Bone/Joint Causes of Leg Pain: • Fracture • Arthritis • Gout/pseudogout
- Differential Diagnosis ... pain/swelling - Fever ... #differential #diagnosis ... lower #extremity #msk ... #physicalexam
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... Presentation: • Fever ... index < 2 • EPO Level ... Anemia #oncology #hematology ... #diagnosis #management
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
vs Tumor Lysis Syndrome ... hyperviscosity syndrome ... - 80% have fever ... #TLS #diagnosis ... #management #hematology
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