7 results
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Diagnosis and Management ... survival is 93-95% Pathophysiology ... : 1) T-cell dysfunction ... failure Clinical Features ... Sarcoidosis #Diagnosis #Management
SEPSIS AND SEPTIC SHOCK

DEFINITION AND PATHOPHYSIOLOGY
 • Sepsis: Life-threatening organ dysfunction due to a dysregulated host
DEFINITION AND PATHOPHYSIOLOGY ... • Pathophysiology ... risk death), T-cell ... COMMON CAUSES + ... INITIAL MANAGEMENT
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
bowel or bladder dysfunction ... monophasic Pathophysiology ... Alterations: - Sensory features ... Pleocytosis > 100 cells ... Myelitis #diagnosis #management
IGG-4 RELATED DISEASE

WHAT?
 • A chronic, immune-mediated fibroinflammatory disease with tumefactive infiltration of IgG4+ plasma cells
- Organ dysfunction ... PATHOPHYSIOLOGY ... • Key Features ... • Pancreas: Type ... complement • Classification
Langerhans Cell Histiocytosis (LCH)

Granulomatous Lesions comprising langerin-positive histiocytes and an inflammatory infiltrate can arise in virtually
, a type of dendritic ... various tissues, leading ... : LCH exhibits features ... • Endocrine Dysfunction ... Histiocytosis #Diagnosis #Management
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
cytopenias and organ dysfunction ... hyperinflammatory syndrome caused ... Persistent fever, organ dysfunction ... Types of HLH • ... Pathophysiology
DEMYELINATING DISEASES OF THE CENTRAL NERVOUS SYSTEM

What Are Demyelinating Diseases?
• Conditions that damage myelin, the protective
Oligoclonal bands, cell ... • Clinical Types ... - Symptom management ... autoimmune/infectious causes ... bladder/bowel dysfunction