397 results
SEPSIS AND SEPTIC SHOCK

DEFINITION AND PATHOPHYSIOLOGY
 • Sepsis: Life-threatening organ dysfunction due to a dysregulated host
DEFINITION AND PATHOPHYSIOLOGY ... • Pathophysiology ... • 49 million cases ... COMMON CAUSES + ... all suspected cases
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... 64%) • Renal dysfunction ... (16%) • Shock ... Treat primary cause ... Coagulation #diagnosis #causes
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Infection/Sepsis/Shock ... Etiology: • Pathophysiology ... unclear, endothelial dysfunction ... the underlying cause ... with AEDs until cause
Shock - Pathophysiology 
Inadequate tissue perfusion to meet O2, nutrient requirements
1. Distributive Shock
2. Hypovolemic Shock
3. Cardiogenic
Shock - Pathophysiology ... Distributive Shock ... Hypovolemic Shock ... #Shock #Pathophysiology ... diagnosis #algorithm #causes
Causes, classification and compensatory responses to shock.

Shock can be caused by any pathological process that leads
Causes, classification ... Shock can be caused ... vasodilatation, myocardial dysfunction ... The cause of shock ... #Differential #Causes
#Pathophysiology #PulmonaryEmbolism #RVDysfunction #Perils #DeathSpiral #Shock #Progression #curbsiders
#Pathophysiology ... PulmonaryEmbolism #RVDysfunction ... #DeathSpiral #Shock
The Death Spiral: Increased RV Afterload (Acute PE) 
#Pathophysiology #PE #PulmonaryEmbolism #Embolism #DeathSpiral #Shock #RVDysfunction #RebelEM
Afterload (Acute PE) #Pathophysiology ... #DeathSpiral #Shock ... #RVDysfunction
Non-lschemic Causes of Cardiogenic Shock:

Beta-Blockers, Calcium Channel Blockers, Digoxin 

Myocarditis 

Cardiomyopathies (sarcoidosis, amyloidosis, Takatsubo, 
hemochromatosis) 

Valvular
Non-lschemic Causes ... of Cardiogenic Shock ... , Sinus nodal dysfunction ... #Nonlschemic #Causes ... #Cardiogenic #Shock
Tachypnea - Differential Diagnosis Framework

Definitions
 • Tachypnea: Respiratory rate > 20/min, shallow breathing in adults
 •
PVFM) Cardiac Causes ... Hematologic Causes ... • Hypovolemic shock ... Severe kidney dysfunction ... Nervous System Dysfunction
Shock Classification Types - Pathophysiology Comparison

Obstructive Shock:
 • Obstructive shock is characterized by a blockage in
Shock Classification ... Types - Pathophysiology ... in blood flow caused ... Depends on the cause ... #Shock #Types #Pathophysiology