14 results
Hemolysis - Diagnostic Algorithm and Causes

Increased red cell production: 
 • Increased Reticulocytosis/polychromasia 
 • Erythroid
Hemolysis - Diagnostic ... #Hemolytic #Anemia ... #Algorithm #Differential ... #Causes #Workup ... #Hematology #Diagnosis
Oncologic Emergencies - Differential Diagnosis Framework

HEMATOLOGIC ONCOLOGIC EMERGENCIES:
Hyperviscosity Syndrome:
 • Spontaneous bleeding
 • Shortness of breath
- Differential ... Diagnosis Framework ... HEMATOLOGIC ... #differential # ... diagnosis #cancer
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential ... Consider sickle cell ... #Anemia #Differential ... #workup #hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
infiltration (e.g. cancer ... defects (e.g. sickle cell ... Production #Index #hematology ... #anemia #differential ... #diagnosis #calculation
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Diagnosis Algorithm ... for workup, including ... blood loss, Acute hemolysis ... , deficiency anemia ... Malignancy: Metastatic cancer
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
fatigue, pallor, dyspnea ... Diagnosis: • hemolytic ... anemia • Cold ... younger pts) Differential ... #anemia #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
- infiltrates (anemia ... • Bone pain, dyspnea ... lymphoid organs When Cancer ... #Leukemia #Hematology ... #Oncology #Diagnosis
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Leukemia - Summary Cancer ... Diagnosis: • ... • Neutropenia, anemia ... #workup #oncology ... #hematology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Cough • Dyspnea ... nodosum • Immune hemolytic ... Hodgkin Lymphoma Workup ... classification #hematology ... #oncology #management
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
• Coombs (-) hemolytic ... anemia due to cold ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology