14 results
Pathophysiology and Effects of Insulin Deficiency

#Insulin #Deficiency #DKA #Ketoacidosis #Diabetes #Pathophysiology #Endocrinology
Pathophysiology ... and Effects of Insulin ... Deficiency #Insulin ... #Deficiency #DKA ... #Endocrinology
Pathogenesis of Diabetic Ketoacidosis - Insulin deficiency or severe insulin insensitivity 

#DKA #Pathophysiology #Endocrinology #Diabetes #Ketoacidosis
Ketoacidosis - Insulin ... deficiency or severe insulin ... insensitivity #DKA ... #Pathophysiology ... #Endocrinology
Pathophysiology of Diabetic Ketoacidosis (DKA) and Hyperglycemic Hyperosmolar Syndrome (HHS)
Absolute Insulin deficit:
 - Type I DM:
Pathophysiology ... Ketoacidosis (DKA ... Polydipsia #dka ... #hhs #pathophysiology ... #comparison #endocrinology
Pathogenesis and Pathophysiology of Diabetic Ketoacidosis (DKA)

DKA is a result of an absolute or relative insulin
Pathogenesis and Pathophysiology ... Ketoacidosis (DKA ... details of the pathophysiology ... #Pathophysiology ... #Diabetes #Endocrinology
Estimating the Total Daily Dose (TDD) of Insulin: Weight-Based Dosing
TDD in units of insulin = N
Dose (TDD) of Insulin ... : Weight-Based Dosing ... #dosing #estimation ... Weight #Based #pharmacology ... #endocrinology
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings
 • Note: in DKA, body K+ is lost
Ketoacidosis (DKA ... along with IV insulin ... +++ fluids. 2) Insulin ... #pathophysiology ... #endocrinology
DPP4 Inhibitors - Normal and Renal Dosing

Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
Normal and Renal Dosing ... -> Stimulates Insulin ... will stimulate insulin ... #Pharmacology # ... Diabetes #DM2 #Endocrinology
SGLT2 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits SGLT2 (sodium/glucose cotransporter 2) in the proximal tubule,
SGLT2 Inhibitors - Pharmacology ... GU infections (e.g ... ketoacidosis (DKA ... SGLT2 #Inhibitors #Pharmacology ... DM2 #diabetes #endocrinology
Insulin Calculations for Type 1 Diabetes 

Insulin-to-Carb Ratio (ICR) 500/TDD = #g of carbs covered by
Insulin Calculations ... Insulin Sensitivity ... calculations used in dosing ... Diabetes #DM1 #Pharmacology ... #Endocrinology
Metformin Pharmacology Summary
Mechanisms of Action:
 • Suppresses gluconeogenesis by the liver
 • Increases insulin-mediated glucose utilization
Metformin Pharmacology ... • Increases insulin-mediated ... side effects (e.g ... #Metformin #Pharmacology ... DM2 #diabetes #endocrinology